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Items 1 to 10 of about 67130
2. Chang YH: Common therapeutic target for both cancer and obesity. World J Biol Chem; 2017 May 26;8(2):102-107

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Common therapeutic target for both cancer and obesity.
  • Obesity and cancer are two interrelated conditions of high epidemiological need, with studies showing that obesity is responsible for nearly 25% of the relative contribution to cancer incidence.
  • Given the connection between these conditions, a drug that can operate on both obesity and cancer is highly desirable.
  • Though this lack of success could be attributed to off-target adverse effects, the underlying causes remain unclear.
  • However, due to insufficient knowledge of the biological functions of N-terminal protein processing, it is hard to predict whether these novel inhibitors would successfully pass clinical trials and thereby benefit cancer and obesity patients.

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  • (PMID = 28588753.001).
  • [ISSN] 1949-8454
  • [Journal-full-title] World journal of biological chemistry
  • [ISO-abbreviation] World J Biol Chem
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Angiogenesis / Cancer / Diabetes / Methionine aminopeptidase / Obesity / Protein maturation / Protein modification / Protein processing / Protein stability
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3. Berthoud HR, Münzberg H, Morrison CD: Blaming the Brain for Obesity: Integration of Hedonic and Homeostatic Mechanisms. Gastroenterology; 2017 May;152(7):1728-1738
MedlinePlus Health Information. consumer health - Obesity.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Blaming the Brain for Obesity: Integration of Hedonic and Homeostatic Mechanisms.
  • The brain plays a key role in the controls of energy intake and expenditure, and many genes associated with obesity are expressed in the central nervous system.
  • This new conceptual framework has several important implications for the treatment of obesity.
  • Because much of this interactive neural processing is outside awareness, cognitive restraint in a world of plenty is made difficult and prevention and treatment of obesity should be more rationally directed to the complex and often redundant mechanisms underlying this interaction.
  • [MeSH-major] Body Weight. Brain / physiopathology. Eating. Energy Metabolism. Homeostasis. Obesity / physiopathology

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Body Weight.
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  • [Copyright] Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.
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  • (PMID = 28192106.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK092587; United States / NIDDK NIH HHS / DK / R01 DK081563; United States / NIDDK NIH HHS / DK / R01 DK071082; United States / NIDDK NIH HHS / DK / R01 DK105032; United States / NIDDK NIH HHS / DK / R01 DK047348
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Appetite / Cognition / Cortex / Hypothalamus / Limbic System / Physical Activity / Reward / Self-Control
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4. Chaparro MP, Harrison GG, Wang MC, Seto EY, Pebley AR: The unhealthy food environment does not modify the association between obesity and participation in the Supplemental Nutrition Assistance Program (SNAP) in Los Angeles County. BMC Public Health; 2017 Jan 14;17(1):81
MedlinePlus Health Information. consumer health - Obesity.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The unhealthy food environment does not modify the association between obesity and participation in the Supplemental Nutrition Assistance Program (SNAP) in Los Angeles County.
  • BACKGROUND: Participation in the Supplemental Nutrition Assistance Program (SNAP) has been linked to an increased risk of obesity, but not much is known about the mechanisms behind this association.
  • The objective of this study was to determine if the neighborhood density of unhealthy food outlets modifies the association between obesity and participation in SNAP.
  • METHODS: Data comes from the first wave of the Los Angeles Family and Neighborhood Survey; included are a subsample of adults (18+ years) who were SNAP participants or eligible non-participants (N = 1,176).
  • We carried out multilevel analyses with obesity (BMI ≥ 30 Kg/m<sup>2</sup>), SNAP participation, and the neighborhood density of unhealthy food outlets as dependent, independent and modifying variables, respectively, controlling for age, gender, race/ethnicity, marital status, working status, mental health, and neighborhood poverty.
  • RESULTS: SNAP participants had double the odds of obesity compared to eligible non-participants (OR = 2.02; 95%CI = 1.44-2.83).
  • CONCLUSIONS: SNAP participation was associated with higher odds of obesity in our primarily Hispanic sample in Los Angeles County, with no effect modification found for the unhealthy portion of the food environment.
  • Additional research is needed to elucidate the mechanisms linking SNAP participation and obesity as they remain unclear.
  • [MeSH-major] Food Assistance / statistics & numerical data. Food Supply / statistics & numerical data. Obesity / epidemiology. Residence Characteristics / statistics & numerical data

  • Genetic Alliance. consumer health - Obesity.
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  • (PMID = 28088219.001).
  • [ISSN] 1471-2458
  • [Journal-full-title] BMC public health
  • [ISO-abbreviation] BMC Public Health
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P2C HD041022
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Effect modification / Food environment / Los Angeles County / Multilevel analysis / Obesity / SNAP
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5. Zubiaurre PR, Bahia LR, da Rosa MQM, Assumpção RP, Padoin AV, Sussembach SP, da Silva EN, Mottin CC: Estimated Costs of Clinical and Surgical Treatment of Severe Obesity in the Brazilian Public Health System. Obes Surg; 2017 Dec;27(12):3273-3280

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Estimated Costs of Clinical and Surgical Treatment of Severe Obesity in the Brazilian Public Health System.
  • BACKGROUND: Obesity is a major global epidemic and a burden to society and health systems.
  • This study aimed to estimate and compare the anual costs of clinical and surgical treatment of severe obesity from the perspective of the Brazilian Public Health System.
  • Participants were divided in clinical (waiting list for a bariatric surgery) and surgical groups (open Roux-en-Y gastric bypass), and then allocated by the time of surgery (up to 1 year; 1-2 years; 2-3 years; and >3 years).
  • Data on non-medical costs, such as transportation, special diets, and caregivers, were also colleted.

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  • (PMID = 28717859.001).
  • [ISSN] 1708-0428
  • [Journal-full-title] Obesity surgery
  • [ISO-abbreviation] Obes Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Bariatric surgery / Costs and cost analysis / Healthcare costs / Obesity
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6. Balasubramanian BA, Garcia MP, Corley DA, Doubeni CA, Haas JS, Kamineni A, Quinn VP, Wernli K, Zheng Y, Skinner CS: Racial/ethnic differences in obesity and comorbidities between safety-net- and non safety-net integrated health systems. Medicine (Baltimore); 2017 Mar;96(11):e6326
MedlinePlus Health Information. consumer health - Obesity.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Racial/ethnic differences in obesity and comorbidities between safety-net- and non safety-net integrated health systems.
  • Little is known about patterns of racial/ethnic disparities between safety-net and non safety-net integrated health systems.We evaluated racial/ethnic differences in body mass index (BMI) and the Charlson comorbidity index from 3 non safety-net- and 1 safety-net integrated health systems in a cross-sectional study.
  • Higher proportions of safety-net versus non safety-net patients had comorbidity score of 3+ (11.1% vs. 5.0%) and BMI ≥35 (27.7% vs. 15.8%).
  • Whites were more likely than blacks or Hispanics to have higher comorbidity scores in a safety net system, but less likely to have higher scores in the non safety-nets.
  • The odds of comorbidity score 3+ and BMI 35+ in blacks relative to whites were significantly lower in safety-net than in non safety-net settings.Racial/ethnic differences were present within both safety-net and non safety-net integrated health systems, but patterns differed.
  • Understanding patterns of racial/ethnic differences in health outcomes in safety-net and non safety-net integrated health systems is important to tailor interventions to eliminate racial/ethnic disparities in health and health care.
  • [MeSH-major] Healthcare Disparities / ethnology. Obesity / ethnology. Safety-net Providers / statistics & numerical data

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Health Disparities.
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  • (PMID = 28296752.001).
  • [ISSN] 1536-5964
  • [Journal-full-title] Medicine
  • [ISO-abbreviation] Medicine (Baltimore)
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U54 CA163261; United States / NCI NIH HHS / CA / U54 CA163262; United States / NCI NIH HHS / CA / U54 CA163308; United States / NCI NIH HHS / CA / U54 CA163313
  • [Publication-type] Journal Article; Observational Study
  • [Publication-country] United States
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7. Vats MG, Mahboub BH, Al Hariri H, Al Zaabi A, Vats D: Obesity and Sleep-Related Breathing Disorders in Middle East and UAE. Can Respir J; 2016;2016:9673054
MedlinePlus Health Information. consumer health - Obesity.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Obesity and Sleep-Related Breathing Disorders in Middle East and UAE.
  • A pandemic of obesity is sweeping all across the globe and the Middle East region also does not remain untouched by this prevailing pandemic.
  • In fact, as per WHO report, Kuwait has the second highest obesity prevalence followed closely by other Middle East (ME) countries, namely, Qatar, Saudi Arabia, and United Arab Emirates (UAE).
  • Apart from direct medical, psychological, and quality of life related adverse effects of obesity, many indirect medical comorbidities, namely, obstructive sleep apnea (OSA), obesity hypoventilation syndrome (OHS), diabetes mellitus (DM), hypertension (HTN), and metabolic syndrome, imposes a significant health burden on the individual and community with consequent morbidity and mortality.
  • The purpose of this review is to shed light on the very high prevalence of obesity, undiagnosed sleep apnea, and other obesity related disorders with discussion of the contributing factors specific to the region including the fair insight into the current status of sleep medicine services in Middle East and UAE despite huge number of patients having undiagnosed sleep disorders.
  • We will also suggest to control this epidemic of obesity and OSA so that the corrective measure could be taken at health ministry level to help people of this region to fight against obesity and related disorders, primarily OSA.
  • [MeSH-major] Obesity / epidemiology. Sleep Apnea, Obstructive / epidemiology

  • Genetic Alliance. consumer health - Obesity.
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  • (PMID = 28070158.001).
  • [ISSN] 1916-7245
  • [Journal-full-title] Canadian respiratory journal
  • [ISO-abbreviation] Can. Respir. J.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Egypt
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8. Dias PC, Henriques P, Anjos LAD, Burlandy L: Obesity and public policies: the Brazilian government's definitions and strategies. Cad Saude Publica; 2017 Jul 27;33(7):e00006016
MedlinePlus Health Information. consumer health - Obesity.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Obesity and public policies: the Brazilian government's definitions and strategies.
  • [Transliterated title] Obesidade e políticas públicas: concepções e estratégias adotadas pelo governo brasileiro.
  • The study analyzes national strategies for dealing with obesity in Brazil in the framework of the Brazilian Unified National Health System (SUS) and the Food and Nutritional Security System (SISAN).
  • Based on the document analysis method, we examined government documents produced in the last 15 years in the following dimensions: definitions of obesity, proposed actions, and strategies for linkage between sectors.
  • In the SUS, obesity is approached as both a risk factor and a disease, with individual and social/environmental approaches aimed at changing eating practices and physical activity.
  • In the SISAN, obesity is also conceived as a social problem involving food insecurity, and new modes of producing, marketing, and consuming foods are proposed to change eating practices in an integrated way.
  • Proposals in the SUS point to an integrated and intra-sector approach to obesity, while those in SISAN emphasize the problem's inter-sector nature from an expanded perspective that challenges the prevailing sector-based institutional structures.
  • [MeSH-major] Health Promotion / trends. National Health Programs / trends. Nutrition Policy / trends. Obesity / prevention & control

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  • (PMID = 28767957.001).
  • [ISSN] 1678-4464
  • [Journal-full-title] Cadernos de saude publica
  • [ISO-abbreviation] Cad Saude Publica
  • [Language] por; eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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9. Palmer W, Henderson D, Stahnke B, Shary K, Hardy T, Welsh JA: Evaluating the Impact of Training in Obesity Prevention Methods on the Counseling, Knowledge, and Skills of WIC Nutritionists in Georgia, 2014-2015. Public Health Rep; 2017 Nov/Dec;132(2_suppl):16S-23S

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluating the Impact of Training in Obesity Prevention Methods on the Counseling, Knowledge, and Skills of WIC Nutritionists in Georgia, 2014-2015.
  • We evaluated the impact of a training program on knowledge and adoption of evidence-based obesity prevention counseling strategies among counselors from Georgia's Special Supplemental Nutrition Program for Women, Infants, and Children (WIC).
  • METHODS: Between July 2014 and September 2015, Children's Healthcare of Atlanta's Strong4Life program provided 388 WIC counselors in Georgia with a 2-hour training session on motivational interviewing, patient-centered counseling, and goal setting for obesity prevention.
  • [MeSH-major] Counseling / education. Counseling / methods. Health Promotion / methods. Motivation. Nutritionists / education. Nutritionists / psychology. Obesity / prevention & control

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  • (PMID = 29136485.001).
  • [ISSN] 1468-2877
  • [Journal-full-title] Public health reports (Washington, D.C. : 1974)
  • [ISO-abbreviation] Public Health Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; WIC / goal setting / motivational interviewing / nutrition / patient-centered counseling
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