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Items 1 to 10 of about 4774
1. Mokarram P, Mohammadi Z, Khazayel S, Dayong Z: Induction of Epigenetic Alteration by CPUK02, An Ent- kaurenoid Derivative of Stevioside. Avicenna J Med Biotechnol; 2017 Jan-Mar;9(1):13-18
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  • BACKGROUND: Dietary polyphenols, such as those found in green tea and red wine, are linked to antitumor activity.

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  • (PMID = 28090275.001).
  • [ISSN] 2008-2835
  • [Journal-full-title] Avicenna journal of medical biotechnology
  • [ISO-abbreviation] Avicenna J Med Biotechnol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Keywords] NOTNLM ; 5-AZA / Colorectal neoplasm / DNMT / Epigenetic / Methylation
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2. Giamogante F, Marrocco I, Romaniello D, Eufemi M, Chichiarelli S, Altieri F: Comparative Analysis of the Interaction between Different Flavonoids and PDIA3. Oxid Med Cell Longev; 2016;2016:4518281
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  • Flavonoids, plant secondary metabolites present in fruits, vegetables, and products such as tea and red wine, show antioxidant, anti-inflammatory, antithrombotic, antiviral, and antitumor activity.
  • The binding site is probably similar but not equivalent to that of green tea catechins, which, as previously demonstrated, can bind to PDIA3 and prevent its interaction with DNA.

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  • (PMID = 28044092.001).
  • [ISSN] 1942-0994
  • [Journal-full-title] Oxidative medicine and cellular longevity
  • [ISO-abbreviation] Oxid Med Cell Longev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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3. Seo EJ, Wu CF, Ali Z, Wang YH, Khan SI, Walker LA, Khan IA, Efferth T: Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells. Front Pharmacol; 2016;7:398
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  • [Title] Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells.
  • : Green tea consumption is associated with chemoprevention of many cancer types.
  • Fresh tea leaves are rich in polyphenolic catechins, which can constitute up to 30% of the dry leaf weight.
  • While the polyphenols of green tea have been well investigated, it is still largely unknown, whether or not non-phenolic constituents also reveal chemopreventive and anti-metastatic effects.
  • In this study, we investigated the effects of a fraction of green tea rich in phenolic compounds (PF), a non-phenolic fraction (NPF), which contains glyceroglycolipids (GGL), and a pure glyceroglycolipid compound isolated from the non-phenolic fraction in human cancer.
  • Dried green tea leaves were extracted and applied to a Sephadex LH-20 column.
  • The resazurin reduction assay was used to investigate the cytotoxicity of green tea samples toward human HepG2 hepatocellular carcinoma and normal AML12 hepatocytes cells.
  • The scratch migration assay was used to investigate the effects of green tea samples on cell migration <i>in vitro</i>.
  • PF and NPF were prepared from methanol extract of green tea.
  • All three green tea samples did not show significant cytotoxic activity up to 10 μg/mL in both HepG2 and AML12 cells, whereas cytotoxicity of the control drug doxorubicin was observed with both cell lines (IC<sub>50</sub> on AML12: 0.024 μg/mL, IC<sub>50</sub> on HepG2: 2.103 μg/mL).
  • We identified three sets of genes differentially expressed upon treatment with the green tea samples.
  • HepG2 and U2OS cells treated with green tea extracts showed the delayed closures.
  • Besides, the number of distinct tubulin filaments decreased upon treatment with green tea samples.
  • We identified not only PF, but also glyceroglycolipids in NPF as contributing factors to the chemopreventive effects of green tea.
  • Both PF and NPF of green tea inhibited cancer cell migration by the disassembly of microtubules, even though they were not cytotoxic.

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  • (PMID = 28194107.001).
  • [Journal-full-title] Frontiers in pharmacology
  • [ISO-abbreviation] Front Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; chemoprevention / green tea / microarray / nutrigenomics / theaceae
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4. Beaudoin Cloutier C, Goyer B, Perron C, Guignard R, Larouche D, Moulin VJ, Germain L, Gauvin R, Auger FA: In Vivo Evaluation and Imaging of a Bilayered Self-Assembled Skin Substitute Using a Decellularized Dermal Matrix Grafted on Mice. Tissue Eng Part A; 2017 Feb 01;
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  • Green fluorescent protein-transfected keratinocytes were also used to follow grafted tissues weekly for 6 weeks using an in vivo imaging system (IVIS).

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  • (PMID = 27958884.001).
  • [ISSN] 1937-335X
  • [Journal-full-title] Tissue engineering. Part A
  • [ISO-abbreviation] Tissue Eng Part A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; autologous / culture techniques / organoid / regenerative medicine / skin equivalent / tissue culture
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5. Li J, Sapper TN, Mah E, Moller MV, Kim JB, Chitchumroonchokchai C, McDonald JD, Bruno RS: Green tea extract treatment reduces NFκB activation in mice with diet-induced nonalcoholic steatohepatitis by lowering TNFR1 and TLR4 expression and ligand availability. J Nutr Biochem; 2017 Mar;41:34-41
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  • [Title] Green tea extract treatment reduces NFκB activation in mice with diet-induced nonalcoholic steatohepatitis by lowering TNFR1 and TLR4 expression and ligand availability.
  • We hypothesized that antiinflammatory activities of green tea extract (GTE) during NASH would lower tumor necrosis factor receptor-1 (TNFR1)- and Toll-like receptor-4 (TLR4)-mediated NFκB activation.
  • These data suggest that dietary GTE treatment reduces hepatic inflammation in NASH by decreasing proinflammatory signaling through TNFR1 and TLR4 that otherwise increases NFκB activation and liver injury.

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  • [Copyright] Copyright © 2016 Elsevier Inc. All rights reserved.
  • (PMID = 28038359.001).
  • [ISSN] 1873-4847
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Green tea / Inflammation / NASH / Nonalcoholic steatohepatitis / TLR4 / TNFR1
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6. Parodi S, Merlo DF, Stagnaro E, Working Group for the Epidemiology of Hematolymphopoietic Malignancies in Italy: Coffee and tea consumption and risk of leukaemia in an adult population: A reanalysis of the Italian multicentre case-control study. Cancer Epidemiol; 2017 Jan 30;47:81-87
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  • [Title] Coffee and tea consumption and risk of leukaemia in an adult population: A reanalysis of the Italian multicentre case-control study.
  • BACKGROUND: Coffee and tea are the most frequently consumed beverages in the world.
  • METHODS: The present investigation is aimed at evaluating the potential role of regular coffee and tea intake on the risk of adult leukaemia by reanalysing a large population based case-control study carried out in Italy, a country with a high coffee consumption and a low use of green tea.
  • Association between Acute Myeloid Leukaemia (AML), Acute Lymphoid Leukaemia, Chronic Myeloid Leukaemia, Chronic Lymphoid Leukaemia, and use of coffee and tea was evaluated by standard logistic regression.
  • A small protective effect of tea intake was found among myeloid malignancies, which was more evident among AML (OR=0.68, 95%CI: 0.49-0.94).
  • The protective effect of tea on the AML risk is only partly consistent with results from other investigations.

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  • [Copyright] Copyright © 2017 Elsevier Ltd. All rights reserved.
  • (PMID = 28153669.001).
  • [ISSN] 1877-783X
  • [Journal-full-title] Cancer epidemiology
  • [ISO-abbreviation] Cancer Epidemiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Adult leukaemia / Case-control study / Coffee / Lymphoid malignancies / Myeloid malignancies / Tea
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7. Matsuo T, Miyata Y, Asai A, Sagara Y, Furusato B, Fukuoka J, Sakai H: Green Tea Polyphenol Induces Changes in Cancer-Related Factors in an Animal Model of Bladder Cancer. PLoS One; 2017;12(1):e0171091
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  • [Title] Green Tea Polyphenol Induces Changes in Cancer-Related Factors in an Animal Model of Bladder Cancer.
  • Green tea polyphenol (GTP) suppresses carcinogenesis and aggressiveness in many types of malignancies including bladder cancer.

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  • (PMID = 28141864.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Fazly Bazzaz BS, Sarabandi S, Khameneh B, Hosseinzadeh H: Effect of Catechins, Green tea Extract and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria. J Pharmacopuncture; 2016 Dec;19(4):312-318
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  • [Title] Effect of Catechins, Green tea Extract and Methylxanthines in Combination with Gentamicin Against Staphylococcus aureus and Pseudomonas aeruginosa: - Combination therapy against resistant bacteria.
  • Green tea catechins, the major green tea polyphenols, show antimicrobial activity against resistant pathogens.
  • The present study aimed to investigate the effect of catechins, green tea extract, and methylxanthines in combination with gentamicin against standard and clinical isolates of <i>Staphylococcus aureus</i> (<i>S. aureus</i>) and the standard strain of <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>).
  • The interactions of green tea extract, epigallate catechin, epigallocatechin gallate, two types of methylxanthine, caffeine, and theophylline with gentamicin were studied <i>in vitro</i> by using a checkerboard method and calculating the fraction inhibitory concentration index (FICI).
  • Green tea extract showed insufficient antibacterial activity when used alone.
  • When green tea extract and catechins were combined with gentamicin, the MIC values of gentamicin against the standard strains and a clinical isolate were reduced, and synergistic activities were observed (FICI < 1).
  • CONCLUSION: The results of the present study revealed that green tea extract and catechins potentiated the antimicrobial action of gentamicin against some clinical isolates of <i>S. aureus</i> and standard <i>P. aeruginosa</i> strains.

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  • (PMID = 28097041.001).
  • [ISSN] 2093-6966
  • [Journal-full-title] Journal of pharmacopuncture
  • [ISO-abbreviation] J Pharmacopuncture
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Keywords] NOTNLM ; Pseudomonas aeruginosa / Staphylococcus aureus / catechins / gentamicin / methylxanthine / antimicrobial resistant
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9. Ni CX, Gong H, Liu Y, Qi Y, Jiang CL, Zhang JP: Green Tea Consumption and the Risk of Liver Cancer: A Meta-Analysis. Nutr Cancer; 2017 Feb-Mar;69(2):211-220
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  • [Title] Green Tea Consumption and the Risk of Liver Cancer: A Meta-Analysis.
  • : Green tea is a commonly consumed beverage in Asia and has been suggested to have anticarcinogenic properties.
  • To date, epidemiological evidence of the effect of green tea consumption on liver cancer risk remains ambiguous.
  • The aim of this meta-analysis is to evaluate the association between green tea consumption and the risk of liver cancer.
  • The summary relative risk for the highest consumption (≥5 cups/day) of green tea on liver cancer incidence compared with nondrinkers was 0.62 (95% confidence interval: 0.49-0.79).
  • We also found a trend that the incidence of liver cancer was reduced with the increasing years of green tea intake (significance at >20 yr).
  • A significant dose-response association was found between green tea drinking and liver cancer risk.
  • The downward trend was most obvious when the consumption of green tea increased up to about 4 cups/day.
  • The results showed that the increasing green tea intake may have a preventive effect against liver cancer.

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  • (PMID = 28095030.001).
  • [ISSN] 1532-7914
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Mombaini E, Jafarirad S, Husain D, Haghighizadeh MH, Padfar P: The Impact of Green Tea Supplementation on Anthropometric Indices and Inflammatory Cytokines in Women with Polycystic Ovary Syndrome. Phytother Res; 2017 Feb 28;
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The Impact of Green Tea Supplementation on Anthropometric Indices and Inflammatory Cytokines in Women with Polycystic Ovary Syndrome.
  • The present study aimed to determine the effect of a green tea supplement on anthropometric indices and inflammatory factors in women with polycystic ovary syndrome (PCOS).
  • In this randomized clinical trial, 45 women with PCOS were randomly allocated into two groups receiving green tea tablets or placebo.
  • The mean of body mass index, weight, waist circumference, and body fat percentage in the green tea group were reduced significantly.
  • The present results suggest that daily consumption of green tea tablets did not cause any effect on inflammation biomarkers in PCOS women.

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  • [Copyright] Copyright © 2017 John Wiley & Sons, Ltd.
  • (PMID = 28244612.001).
  • [ISSN] 1099-1573
  • [Journal-full-title] Phytotherapy research : PTR
  • [ISO-abbreviation] Phytother Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; anthropometric indices / green tea / inflammatory factors / polycystic ovary syndrome
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