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Items 1 to 10 of about 60752
1. Xu XX, Zhang XH, Diao Y, Huang YX: Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro. Kaohsiung J Med Sci; 2017 Feb;33(2):62-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.
  • : Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties.
  • In the present study, protective effects of A. bidentata saponins (ABS) on inflammation and apoptosis in interleukine-1β (IL-1β)-induced chondrocytes were investigated.
  • IL-1β-induced inflammation and matrix degradation were also alleviated by ABS through the downregulation of the expressions of matrix metalloproteinases 3 and 9 and cyclooxygenase-2.

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  • [Copyright] Copyright © 2016. Published by Elsevier Taiwan.
  • (PMID = 28137413.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Keywords] NOTNLM ; Achyranthes bidentata saponins / Apoptosis / Chondrocyte / Inflammation / Osteoarthritis
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2. Sakthirajan R, Dhanapriya J, Dineshkumar T, Gopalakrishnan N, Murugan S, Balasubramaniyan T: Thrombotic microangiopathy: An unusual cause of renal failure in rheumatoid arthritis. Indian J Nephrol; 2017 Jan-Feb;27(1):81-83
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  • [Title] Thrombotic microangiopathy: An unusual cause of renal failure in rheumatoid arthritis.
  • Rheumatoid arthritis (RA) is one of the commonest rheumatological diseases.
  • Renal involvement is not common but can occur as a result of chronic inflammation as part of disease process or drug toxicity.

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  • (PMID = 28182045.001).
  • [ISSN] 0971-4065
  • [Journal-full-title] Indian journal of nephrology
  • [ISO-abbreviation] Indian J Nephrol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Keywords] NOTNLM ; Hemodialysis / plasmapheresis / renal biopsy / rheumatoid arthritis
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3. Pan X, Lopez-Olivo MA, Song J, Pratt G, Suarez-Almazor ME: Systematic review of the methodological quality of controlled trials evaluating Chinese herbal medicine in patients with rheumatoid arthritis. BMJ Open; 2017 Mar 01;7(3):e013242
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Systematic review of the methodological quality of controlled trials evaluating Chinese herbal medicine in patients with rheumatoid arthritis.
  • OBJECTIVES: We appraised the methodological and reporting quality of randomised controlled clinical trials (RCTs) evaluating the efficacy and safety of Chinese herbal medicine (CHM) in patients with rheumatoid arthritis (RA).

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  • [Copyright] Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
  • (PMID = 28249848.001).
  • [ISSN] 2044-6055
  • [Journal-full-title] BMJ open
  • [ISO-abbreviation] BMJ Open
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Chinese herbal medicine / Quality of randomized controlled trials / Rheumatoid arthritis / Systematic review / Traditional Chinese medicine
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4. Bahadori S, Ahmadzadeh A, Shams Ardekani MR, Kamalinejad M, Keshavarz M, Salamzadeh J: Does Regular Use of a Complementary Medicine of <i>Olea Europe</i> and <i>Ficus carica</i> Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate? Iran J Pharm Res; 2016;15(4):933-940
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does Regular Use of a Complementary Medicine of <i>Olea Europe</i> and <i>Ficus carica</i> Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate?
  • Rheumatoid arthritis (RA) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role.
  • In this study, the lipid profile and fasting blood sugar (FBS) of RA patients receiving a complementary medicine of olive and fig, as add-on therapy for routine disease-modifying antirheumatic drugs (DMARDs) regimen containing low dose methotrexate (MTX), were studied.
  • Our findings are more reassuring for patients and their doctors to trust on the safety of the investigated complementary preparation to be used as add-on therapy to manage rheumatoid arthritis.

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  • (PMID = 28243292.001).
  • [ISSN] 1735-0328
  • [Journal-full-title] Iranian journal of pharmaceutical research : IJPR
  • [ISO-abbreviation] Iran J Pharm Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Keywords] NOTNLM ; Fasting blood sugar / Fig / Lipid profile / Olive / Rheumatoid arthritis
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5. Zhao P, Chen KL, Zhang GL, Deng GR, Li J: Pharmacological Basis for Use of &lt;i&gt;Selaginella moellendorffii&lt;/i&gt; in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition. Evid Based Complement Alternat Med; 2017;2017:2103254
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacological Basis for Use of <i>Selaginella moellendorffii</i> in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition.
  • This study was aimed at evaluating the effects of <i>Selaginella moellendorffii</i> Hieron. (SM) on gouty arthritis and getting an insight of the possible mechanisms.
  • The paw oedema, the neutrophil accumulation, inflammatory mediators, lipid peroxidation, and histopathological changes of the joints were analyzed in gouty arthritis rat model, and the kidney injury and serum urate were detected in hyperuricemic mice.
  • The high dose of SM extract could significantly prevent the paw swelling, reduce gouty joint inflammatory features, reduce the release of IL-1<i>β</i> and TNF-<i>α</i>, lower malondialdehyde (MDA) and myeloperoxidase (MPO) levels, and increase superoxide dismutase (SOD) level (<i>P</i> < 0.01).

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  • (PMID = 28250791.001).
  • [ISSN] 1741-427X
  • [Journal-full-title] Evidence-based complementary and alternative medicine : eCAM
  • [ISO-abbreviation] Evid Based Complement Alternat Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Curtis JR, Schulze-Koops H, Takiya L, Mebus CA, Terry KK, Biswas P, Jones TV: Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis. Clin Exp Rheumatol; 2017 Jan 04;
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  • [Title] Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis.
  • OBJECTIVES: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA).

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  • (PMID = 28079500.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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7. Chen Y, Wang QW, Zuo J, Chen JW, Li X: Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice. BMC Complement Altern Med; 2017 Jan 05;17(1):11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice.
  • BACKGROUND: Claoxylon indicum Hassk. (Euphorbiaceae), named Diu Le Bang, have functions of dehumidification and relieving swelling pain, and is used as a folk medicine to treat Rheumatoid arthritis (RA), lumbocrural pain and foot edema in the south of China.
  • The aim of the present study was to investigate the anti-arthritic activity of the ethanol extract of Claoxylon indicum (CIE) on mice with adjuvant induced joint arthritis.
  • METHODS: Adjuvant arthritis was induced in mice by subcutaneous injection of complete Freund's adjuvant into the plantar surface of right hind paw.
  • Arthritis severity was evaluated by arthritic score, hind paws oedema and spleen index, and histological examinations.
  • RESULTS: CIE administration (0.4 and 0.8 g/kg) suppressed the inflammatory responses in the joints of adjuvant-induced arthritis (AIA) mice, suggested by the modulatory effects on paw swelling, hyperplasia of lymphatic tissues and synovial membrane.
  • [MeSH-major] Antirheumatic Agents / administration & dosage. Arthritis, Experimental / drug therapy. Drugs, Chinese Herbal / administration & dosage. Euphorbiaceae / chemistry

  • Genetic Alliance. consumer health - Arthritis.
  • Hazardous Substances Data Bank. ETHANOL .
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  • (PMID = 28056924.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Drugs, Chinese Herbal; 0 / Interleukin-1beta; 0 / Tumor Necrosis Factor-alpha; 3K9958V90M / Ethanol; 9007-81-2 / Freund's Adjuvant
  • [Keywords] NOTNLM ; Adjuvant arthritis / Claoxylon indicum / Inflammation / Rheumatoid arthritis (RA)
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8. Gao S, Wang Q, Tian XH, Li HL, Shen YH, Xu XK, Wu GZ, Hu ZL, Zhang WD: Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis. J Ethnopharmacol; 2017 Jan 20;196:39-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis.
  • BACKGROUNDS: Inula helenium L. is an herb with anti-inflammatory properties.
  • However, the anti-inflammatory effects of SL-containing extracts of I. helenium have not been explored.
  • Here we prepared total SLs from I. helenium (TSL-IHL), analyzed its chemical constituents, and performed cellular and animal studies to evaluate its anti-inflammatory activities.
  • Its in vitro effects on the activation of signaling pathways and expression of inflammatory genes were examined by western blotting and quantitative real-time PCR, respectively, and compared with those of AL and IAL.
  • Its in vivo anti-inflammatory effects were evaluated in adjuvant- and collagen-induced arthritis rat models.
  • Oral administration of TSL-IHL at 12.5-50mg/kg could dose-dependently alleviate the arthritic severity and paw swelling in either developing or developed phases of arthritis of rats induced by adjuvant or collagen CONCLUSIONS: These results indicated potentials of TSL-IHL in prevention and therapy of rheumatoid arthritis.

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  • [Copyright] Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 27988396.001).
  • [ISSN] 1872-7573
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Keywords] NOTNLM ; Anti-inflammatory / Inula helenium L. / Rheumatoid arthritis / Total sesquiterpene lactones
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9. Barra LJ, Pope JE, Hitchon C, Boire G, Schieir O, Lin D, Thorne CJ, Tin D, Keystone EC, Haraoui B, Jamal S, Bykerk VP, CATCH group: The effect of rheumatoid arthritis-associated autoantibodies on the incidence of cardiovascular events in a large inception cohort of early inflammatory arthritis. Rheumatology (Oxford); 2017 Jan 09;
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The effect of rheumatoid arthritis-associated autoantibodies on the incidence of cardiovascular events in a large inception cohort of early inflammatory arthritis.
  • METHODS: Patients were enrolled in the Canadian Early Inflammatory Arthritis Cohort, a prospective multicentre inception cohort.
  • RESULTS: A total of 2626 patients were included: the mean symptom duration at diagnosis was 6.3 months (sd 4.6), the mean age was 53 years (sd 15), 72% were female and 86% met classification criteria for RA.
  • Baseline covariates independently associated with incident CVEs were older age, a history of hypertension and a longer duration of RA symptoms prior to diagnosis.
  • CONCLUSION: The rate of CVEs early in the course of inflammatory arthritis was low; however, delays in the diagnosis of arthritis increased the rate of CVEs.
  • Results support early aggressive management of RA disease activity and co-morbidities to prevent severe complications.

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  • [Copyright] © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
  • (PMID = 28073956.001).
  • [ISSN] 1462-0332
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; ACPA / RF / cardiovascular disease / complications / rheumatoid arthritis / seropositive
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10. Pogacnik Murillo AL, Eckstein F, Wirth W, Beavers D, Loeser RF, Nicklas BJ, Mihalko SL, Miller GD, Hunter DJ, Messier SP: Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs; 2017 Feb 22;
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial.
  • OBJECTIVES: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines.
  • METHODS: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis.

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  • [Copyright] © 2017 S. Karger AG, Basel.
  • (PMID = 28222422.001).
  • [ISSN] 1422-6421
  • [Journal-full-title] Cells, tissues, organs
  • [ISO-abbreviation] Cells Tissues Organs (Print)
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / R01 AR052528
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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