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Items 1 to 10 of about 61786
1. Zhao P, Chen KL, Zhang GL, Deng GR, Li J: Pharmacological Basis for Use of <i>Selaginella moellendorffii</i> in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition. Evid Based Complement Alternat Med; 2017;2017:2103254

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacological Basis for Use of <i>Selaginella moellendorffii</i> in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition.
  • This study was aimed at evaluating the effects of <i>Selaginella moellendorffii</i> Hieron. (SM) on gouty arthritis and getting an insight of the possible mechanisms.
  • The paw oedema, the neutrophil accumulation, inflammatory mediators, lipid peroxidation, and histopathological changes of the joints were analyzed in gouty arthritis rat model, and the kidney injury and serum urate were detected in hyperuricemic mice.
  • The high dose of SM extract could significantly prevent the paw swelling, reduce gouty joint inflammatory features, reduce the release of IL-1<i>β</i> and TNF-<i>α</i>, lower malondialdehyde (MDA) and myeloperoxidase (MPO) levels, and increase superoxide dismutase (SOD) level (<i>P</i> < 0.01).

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  • (PMID = 28250791.001).
  • [ISSN] 1741-427X
  • [Journal-full-title] Evidence-based complementary and alternative medicine : eCAM
  • [ISO-abbreviation] Evid Based Complement Alternat Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. Curtis JR, Schulze-Koops H, Takiya L, Mebus CA, Terry KK, Biswas P, Jones TV: Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis. Clin Exp Rheumatol; 2017 Jan 04;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis.
  • OBJECTIVES: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA).

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  • (PMID = 28079500.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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3. Mbiantcha M, Almas J, Shabana SU, Nida D, Aisha F: Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund's adjuvant-induced arthritis in rats. BMC Complement Altern Med; 2017 Feb 15;17(1):111
MedlinePlus Health Information. consumer health - Rheumatoid Arthritis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund's adjuvant-induced arthritis in rats.
  • BACKGROUND: Rheumatoid arthritis, disease of unknown causes is a rheumatic and autoimmune pathology, recognised for its increasing frequency and its adverse consequences.
  • It is a disease that occurs in most cases between 50 and 60 years and women are more affected than men.
  • This study aimed at evaluating immunomodulatory and anti-arthritis capacity of aqueous and methanol extracts of stem bark of Piptadeniastrum africanum (Mimosaceae).
  • METHODS: ROS production from phagocytes, proliferation of T-cells, TNF-α and IL-1β production and cytotoxicity were performed by using chemiluminescence technique, liquid scintillation counter, ELISA and MTT assay, respectively.
  • Anti-arthritic activity was evaluated using a model of adjuvant induced arthritis.
  • Piptadeniastrum africanum also significantly exhibited antiarthritic activity in complete Freund's adjuvant induced arthritis in rat associated with a significant anti-inflammatory and anti-hyperalgesia activity.
  • CONCLUSIONS: Immunomodulatory, anti-inflammatory, antihyperalgesia and anti-arthritis potential revealed in this study approve that, Piptadeniastrum africanum is a plant rich in compounds with anti-arthritic properties.
  • [MeSH-major] Angiosperms. Anti-Inflammatory Agents / therapeutic use. Antirheumatic Agents / therapeutic use. Arthritis, Experimental / drug therapy. Arthritis, Rheumatoid / drug therapy. Phytotherapy. Plant Extracts / therapeutic use

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  • (PMID = 28202019.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents; 0 / Antioxidants; 0 / Antirheumatic Agents; 0 / Immunologic Factors; 0 / Interleukin-1beta; 0 / Plant Extracts; 0 / Reactive Oxygen Species; 0 / Tumor Necrosis Factor-alpha; 9007-81-2 / Freund's Adjuvant
  • [Keywords] NOTNLM ; Cytotoxicity / Immunomodulation / Oxidative burst / Piptadeniastrum africanum / Rheumatoid arthritis / T-cell proliferation
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4. Chen Y, Wang QW, Zuo J, Chen JW, Li X: Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice. BMC Complement Altern Med; 2017 Jan 05;17(1):11
Hazardous Substances Data Bank. ETHANOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice.
  • BACKGROUND: Claoxylon indicum Hassk. (Euphorbiaceae), named Diu Le Bang, have functions of dehumidification and relieving swelling pain, and is used as a folk medicine to treat Rheumatoid arthritis (RA), lumbocrural pain and foot edema in the south of China.
  • The aim of the present study was to investigate the anti-arthritic activity of the ethanol extract of Claoxylon indicum (CIE) on mice with adjuvant induced joint arthritis.
  • METHODS: Adjuvant arthritis was induced in mice by subcutaneous injection of complete Freund's adjuvant into the plantar surface of right hind paw.
  • Arthritis severity was evaluated by arthritic score, hind paws oedema and spleen index, and histological examinations.
  • RESULTS: CIE administration (0.4 and 0.8 g/kg) suppressed the inflammatory responses in the joints of adjuvant-induced arthritis (AIA) mice, suggested by the modulatory effects on paw swelling, hyperplasia of lymphatic tissues and synovial membrane.
  • [MeSH-major] Antirheumatic Agents / administration & dosage. Arthritis, Experimental / drug therapy. Drugs, Chinese Herbal / administration & dosage. Euphorbiaceae / chemistry

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  • (PMID = 28056924.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Drugs, Chinese Herbal; 0 / Interleukin-1beta; 0 / Tumor Necrosis Factor-alpha; 3K9958V90M / Ethanol; 9007-81-2 / Freund's Adjuvant
  • [Keywords] NOTNLM ; Adjuvant arthritis / Claoxylon indicum / Inflammation / Rheumatoid arthritis (RA)
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5. Hamidpour R, Hamidpour S, Hamidpour M, Shahlari M, Sohraby M, Shahlari N, Hamidpour R: Russian olive (&lt;i&gt;Elaeagnus angustifolia&lt;/i&gt; L.): From a variety of traditional medicinal applications to its novel roles as active antioxidant, anti-inflammatory, anti-mutagenic and analgesic agent. J Tradit Complement Med; 2017 Jan;7(1):24-29

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Russian olive (<i>Elaeagnus angustifolia</i> L.): From a variety of traditional medicinal applications to its novel roles as active antioxidant, anti-inflammatory, anti-mutagenic and analgesic agent.
  • The use of fruit powder and extract of <i>E. angustifolia</i> L. have shown to be effective in alleviating pain in patients with rheumatoid arthritis and also in reducing the healing time of wounds in injured person.
  • In addition, some recent reports have indicated the anti-oxidant, anti-inflammatory, antimicrobial, anticancer and some other properties of oleaster plant.

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  • (PMID = 28053884.001).
  • [Journal-full-title] Journal of traditional and complementary medicine
  • [ISO-abbreviation] J Tradit Complement Med
  • [Language] eng
  • [Publication-type] Review; Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Anti-cancer / Anti-inflammation / Anti-microbial / Anti-oxidant / Russian olive
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6. Rahimi H, Dieudonne G, Kheyfits V, Bouta EM, Wood RW, Barrett R, Moorehead S, Schwarz EM, Ritchlin CT: Relationship Between Lymph Node Volume and Pain Following Certolizumab Therapy for Rheumatoid Arthritis Flare: A Pilot Study. Clin Med Insights Arthritis Musculoskelet Disord; 2016;9:203-208

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relationship Between Lymph Node Volume and Pain Following Certolizumab Therapy for Rheumatoid Arthritis Flare: A Pilot Study.
  • OBJECTIVES: The mechanisms that trigger flare in rheumatoid arthritis (RA) are unknown.
  • In murine arthritis models, dysfunctional lymph node (LN) drainage is associated with joint flare.
  • To examine if LN alterations are associated with RA flare, we analyzed the change in LN volume via contrast-enhanced magnetic resonance imaging (CE-MRI) in patients with active joint flare at baseline and 16 weeks after certolizumab pegol (CZP) therapy.
  • We also assessed the changes in popliteal or epitrochlear LN volumes versus the Rheumatoid and Arthritis Outcome Score (RAOS) (knee), or the Michigan Hand Questionnaire (MHQ; wrist/hand), and Disease Activity Score 28 (DAS28), at baseline and 16 weeks.
  • Moreover, the remarkably linear inverse correlation between LN volume and joint pain observed in this small clinical pilot provides initial evidence to support the concept that dynamic changes in draining LN volume are a biomarker of clinical response to therapy in RA.

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  • (PMID = 28008295.001).
  • [Journal-full-title] Clinical medicine insights. Arthritis and musculoskeletal disorders
  • [ISO-abbreviation] Clin Med Insights Arthritis Musculoskelet Disord
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / P30 AR069655; United States / NIAMS NIH HHS / AR / R01 AR056702
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; lymph node / rheumatoid arthritis / tumor necrosis factor inhibitor
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7. Yao Y, Jiang CS, Sun N, Li WQ, Niu Y, Han HQ, Miao ZH, Zhao XX, Zhao J, Li J: Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes. Molecules; 2017 Jan 10;22(1)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
  • Chemical investigation of <i>Tamarix ramosissima</i> Ledeb, a traditional herbal medicine used for rheumatoid arthritis (RA) treatment in northwest China, led to the discovery of a new phenolic aromatic rings substituted lactam, tamaractam (<b>1</b>), together with the previously reported compounds <i>cis</i>-<i>N</i>-feruloyl-3-<i>O</i>-methyldopamine (<b>2</b>) and <i>trans</i>-<i>N</i>-feruloyl-3-<i>O</i>-methyldopamine (<b>3</b>).
  • [MeSH-major] Apoptosis / drug effects. Arthritis, Rheumatoid / drug therapy. Deoxyepinephrine / chemistry. Lactams / chemistry

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  • (PMID = 28075411.001).
  • [ISSN] 1420-3049
  • [Journal-full-title] Molecules (Basel, Switzerland)
  • [ISO-abbreviation] Molecules
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Lactams; R7339QLN1C / Deoxyepinephrine
  • [Keywords] NOTNLM ; Tamarix ramosissima (major topic) / apoptosis (major topic) / fibroblast-like synoviocytes (major topic) / growth inhibitory activity (major topic) / rheumatoid arthritis (major topic) / tamaractam (major topic)
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8. Talotta R, Atzeni F, Batticciotto A, Benucci M, Bongiovanni S, Sarzi-Puttini P: Biological Agents In Rheumatoid Arthritis: A Cross-Link Between Immune Tolerance And Immune Surveillance. Curr Rheumatol Rev; 2016 Dec 30;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biological Agents In Rheumatoid Arthritis: A Cross-Link Between Immune Tolerance And Immune Surveillance.
  • : The biological drugs have all been successfully used to treat rheumatoid arthritis (RA) and have led to fair rates of clinical remission; however, the possible occurrence of adverse events such as infectious diseases or cancers means that the patients undergoing treatment need to be closely monitored.

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  • (PMID = 28034349.001).
  • [ISSN] 1875-6360
  • [Journal-full-title] Current rheumatology reviews
  • [ISO-abbreviation] Curr Rheumatol Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United Arab Emirates
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9. Martínez-González CL, Martínez L, Martínez-Ortiz EJ, González-Trujano ME, Déciga-Campos M, Ventura-Martínez R, Díaz-Reval I: Moringa oleifera, a species with potential analgesic and anti-inflammatory activities. Biomed Pharmacother; 2017 Mar;87:482-488
Hazardous Substances Data Bank. KAEMPFEROL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Moringa oleifera, a species with potential analgesic and anti-inflammatory activities.
  • The present study was undertaken to examine the antinociceptive and anti-inflammatory spectrum of M. oleifera leaf extracts discriminating the constituents' nature by using different kind of experimental models in rats.
  • Pharmacological evaluation of a non-polar and/or polar extracts at several doses (30-300mg/kg, p.o.) was explored through experimental nociception using formalin test, carrageenan-induced paw edema and arthritis with subcutaneous injection of collagen in rats.
  • Not only polar (from 30 or 100mg/kg, p.o.) but also non-polar extract produced significant inhibition of the nociceptive behavior with major efficacy in the inflammatory response in different assessed experimental models.
  • [MeSH-major] Analgesics / pharmacology. Anti-Inflammatory Agents / pharmacology. Edema / drug therapy. Moringa oleifera / chemistry. Pain / drug therapy

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  • MedlinePlus Health Information. consumer health - Pain.
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  • [Copyright] Copyright © 2016 Elsevier Masson SAS. All rights reserved.
  • (PMID = 28073097.001).
  • [ISSN] 1950-6007
  • [Journal-full-title] Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  • [ISO-abbreviation] Biomed. Pharmacother.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents; 0 / Glucosides; 0 / Kaempferols; 0 / Phytochemicals; 0 / Plant Extracts; 731P2LE49E / kaempferol
  • [Keywords] NOTNLM ; Antinociception (major topic) / Chlorogenic acid (major topic) / Folk medicine (major topic) / Kaempferol-3-glucoside (major topic) / Moringa oleifera (major topic) / Morphology (major topic) / Scanning electronic microscopy (major topic)
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10. Yang M, Guo MY, Luo Y, Yun MD, Yan J, Liu T, Xiao CH: Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial. Chin J Integr Med; 2016 Dec 29;
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial.
  • OBJECTIVE: To investigate the effect and safety of the complementary use of the extract of Artemisia annua L. (EAA) on treating active rheumatoid arthritis (RA).

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  • (PMID = 28035541.001).
  • [ISSN] 1672-0415
  • [Journal-full-title] Chinese journal of integrative medicine
  • [ISO-abbreviation] Chin J Integr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Keywords] NOTNLM ; Artemisia annua / Chinese medicine / leflflunomide / methotrexate / rheumatoid arthritis
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