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Items 1 to 10 of about 62630
1. Curtis JR, Schulze-Koops H, Takiya L, Mebus CA, Terry KK, Biswas P, Jones TV: Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis. Clin Exp Rheumatol; 2017 May-Jun;35(3):390-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis.
  • OBJECTIVES: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA).

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  • (PMID = 28079500.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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2. Calderaro DC, Corrêa JD, Ferreira GA, Barbosa IG, Martins CC, Silva TA, Teixeira AL: Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis. Rev Bras Reumatol Engl Ed; 2017 May - Jun;57(3):238-244

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis.
  • OBJECTIVE: To evaluate the influence of periodontal treatment on rheumatoid arthritis activity.
  • Included articles were: prospective studies; including patients older than 18 years, diagnosed with periodontitis and rheumatoid arthritis submitted to non-surgical periodontal treatment; with a control group receiving no periodontal treatment; with outcomes including at least one marker of rheumatoid arthritis activity.
  • Erythrocyte sedimentation rate, C-reactive protein, patient's assessment of rheumatoid activity using visual analogical scale, tender and swollen joint counts showed a trend toward reduction (not statistically significant).
  • CONCLUSIONS: The reduction of DAS 28 in patients with rheumatoid arthritis after periodontal treatment suggests that the improvement of periodontal condition is beneficial to these patients.
  • Further randomized controlled clinical trials are necessary to confirm this finding.

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  • [Copyright] Copyright © 2016. Published by Elsevier Editora Ltda.
  • (PMID = 28535896.001).
  • [ISSN] 2255-5021
  • [Journal-full-title] Revista brasileira de reumatologia
  • [ISO-abbreviation] Rev Bras Reumatol Engl Ed
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Keywords] NOTNLM ; Artrite reumatoide / Interações doença periodontal-sistêmica / Meta-analysis / Metanálise / Periodontal-systemic disease interactions / Periodontite / Periodontitis / Rheumatoid arthritis
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3. Yao Y, Jiang CS, Sun N, Li WQ, Niu Y, Han HQ, Miao ZH, Zhao XX, Zhao J, Li J: Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes. Molecules; 2017 Jan 10;22(1)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
  • Chemical investigation of <i>Tamarix ramosissima</i> Ledeb, a traditional herbal medicine used for rheumatoid arthritis (RA) treatment in northwest China, led to the discovery of a new phenolic aromatic rings substituted lactam, tamaractam (<b>1</b>), together with the previously reported compounds <i>cis</i>-<i>N</i>-feruloyl-3-<i>O</i>-methyldopamine (<b>2</b>) and <i>trans</i>-<i>N</i>-feruloyl-3-<i>O</i>-methyldopamine (<b>3</b>).
  • [MeSH-major] Apoptosis / drug effects. Arthritis, Rheumatoid / drug therapy. Deoxyepinephrine / chemistry. Lactams / chemistry

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  • (PMID = 28075411.001).
  • [ISSN] 1420-3049
  • [Journal-full-title] Molecules (Basel, Switzerland)
  • [ISO-abbreviation] Molecules
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Lactams; R7339QLN1C / Deoxyepinephrine
  • [Keywords] NOTNLM ; Tamarix ramosissima (major topic) / apoptosis (major topic) / fibroblast-like synoviocytes (major topic) / growth inhibitory activity (major topic) / rheumatoid arthritis (major topic) / tamaractam (major topic)
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4. Ingegnoli F, Carmona L, Castrejon I: Corrigendum to "Systematic review of systemic sclerosis-specific instruments for the EULAR Outcome Measures Library: An evolutional database model of validated patient-reported outcomes [Semin Arthritis Rheum 46(5) (2017) 609-614]. Semin Arthritis Rheum; 2017 Jul 01;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Corrigendum to "Systematic review of systemic sclerosis-specific instruments for the EULAR Outcome Measures Library: An evolutional database model of validated patient-reported outcomes [Semin Arthritis Rheum 46(5) (2017) 609-614].

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  • (PMID = 28676176.001).
  • [ISSN] 1532-866X
  • [Journal-full-title] Seminars in arthritis and rheumatism
  • [ISO-abbreviation] Semin. Arthritis Rheum.
  • [Language] eng
  • [Publication-type] Published Erratum
  • [Publication-country] United States
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5. Lapčević M, Vuković M, Gvozdenović BS, Mioljević V, Marjanović S: Socioeconomic and therapy factor influence on self-reported fatigue, anxiety and depression in rheumatoid arthritis patients. Rev Bras Reumatol; 2017 Feb 27;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Socioeconomic and therapy factor influence on self-reported fatigue, anxiety and depression in rheumatoid arthritis patients.
  • [Transliterated title] Influência de fatores socioeconômicos e de tratamento sobre a fadiga, ansiedade e depressão autorrelatadas em pacientes com artrite reumatoide.
  • INTRODUCTION: Fatigue, anxiety and depression are very frequent symptoms in patients with rheumatoid arthritis (RA).
  • Self-reported patients health status was measured by: Fatigue Assessment Scale, Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7.
  • 1) non-steroidal anti-inflammatory drugs (NSAIDs) and/or analgesics and/or corticosteroids;.
  • 2) synthetic disease-modifying antirheumatic drugs (DMARDs) alone or in combination with corticosteroids and/or NSAIDs and 3) any RA treatment which includes biologic DMARDs.

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  • [Copyright] Copyright © 2017. Published by Elsevier Editora Ltda.
  • (PMID = 28336154.001).
  • [ISSN] 1809-4570
  • [Journal-full-title] Revista brasileira de reumatologia
  • [ISO-abbreviation] Rev Bras Reumatol
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Keywords] NOTNLM ; Ansiedade / Anxiety / Artrite reumatoide / Depression / Depressão / Fadiga / Fatigue / Rheumatoid arthritis / Therapy / Tratamento
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6. Yang M, Guo MY, Luo Y, Yun MD, Yan J, Liu T, Xiao CH: Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial. Chin J Integr Med; 2017 Jul;23(7):496-503
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial.
  • OBJECTIVE: To investigate the effect and safety of the complementary use of the extract of Artemisia annua L. (EAA) on treating active rheumatoid arthritis (RA).

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  • (PMID = 28035541.001).
  • [ISSN] 1672-0415
  • [Journal-full-title] Chinese journal of integrative medicine
  • [ISO-abbreviation] Chin J Integr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Keywords] NOTNLM ; Artemisia annua / Chinese medicine / leflflunomide / methotrexate / rheumatoid arthritis
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7. Viswanath A, Khanduja V: Can hip arthroscopy in the presence of arthritis delay the need for hip arthroplasty? J Hip Preserv Surg; 2017 Jan;4(1):3-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Can hip arthroscopy in the presence of arthritis delay the need for hip arthroplasty?
  • Hip arthroscopy for joint preservation surgery has grown immensely over the last two decades.
  • There is now an increasing trend to try and expand the role of hip arthroscopy to include patients of an older age or perhaps even with signs of arthritis, instead of the established patient group of young adults with mechanical symptoms or serious athletes.
  • Once arthritis is apparent, the arthroscopic procedures needed to try and limit progression of the disease are likely to be different to those needed in young adult non-arthritic hips.
  • Similarly, the expectation of results following an arthroscopic procedure in an older adult with arthritis must also be different.
  • With an almost 5-fold increase in conversion rate from arthroscopy to arthroplasty in the over 50s population, arthroscopy in arthritis is a different procedure, with a different outcome, to arthroscopy in young adults with no evidence of osteoarthritis.
  • This article takes a closer inspection at outcomes following hip arthroscopy in the older population particularly in those with evidence of early arthritis.
  • This paper does not attempt to make recommendations in other diagnoses such as inflammatory arthritis or other secondary arthritides.
  • Although the nature of surgeons is to find new techniques and push boundaries, we highlight the need for caution in undertaking arthroscopic intervention when arthritis is already apparent at presentation.

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  • (PMID = 28630715.001).
  • [ISSN] 2054-8397
  • [Journal-full-title] Journal of hip preservation surgery
  • [ISO-abbreviation] J Hip Preserv Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
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8. Albrecht K, Luque Ramos A, Callhoff J, Hoffmann F, Minden K, Zink A: [Outpatient care and disease burden of rheumatoid arthritis : Results of a linkage of claims data and a survey of insured persons]. Z Rheumatol; 2017 Mar 21;
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Outpatient care and disease burden of rheumatoid arthritis : Results of a linkage of claims data and a survey of insured persons].
  • [Transliterated title] Ambulante Versorgung und Krankheitslast der rheumatoiden Arthritis : Eine Analyse von Abrechnungsdaten und einer Versichertenbefragung.
  • BACKGROUND: Healthcare of patients with rheumatoid arthritis (RA) in Germany has mainly been evaluated in the past in RA cohorts from specialized arthritis centers.
  • A 31-item questionnaire covering patient reported diagnosis, healthcare utilization and burden of illness was sent to a stratified random sample of 6193 insured persons.
  • Data from the respondents regarding rheumatological care and disease status were evaluated.
  • RESULTS: In 2013 and 2014, a total of 96,921 adults with M05 or M06 diagnosis were insured.
  • The questionnaire was answered by 51% of the sample and of these 81% confirmed the RA diagnosis.
  • Treatment with disease-modifying antirheumatic drugs (DMARDs) was 61% (claims data) and 63% (respondents) in persons in rheumatological care but only 18% outside rheumatological care.
  • Patients with higher age and patients with M06 diagnosis had less drug prescriptions and were less frequently treated by rheumatologists.

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  • (PMID = 28324149.001).
  • [ISSN] 1435-1250
  • [Journal-full-title] Zeitschrift fur Rheumatologie
  • [ISO-abbreviation] Z Rheumatol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Diagnostics / Disease burden / Drug treatment / Health care / Rheumatoid arthritis
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9. Baker NA, Barbour KE, Helmick CG, Zack M, Al Snih S: Arthritis and cognitive impairment in older adults. Rheumatol Int; 2017 Jun;37(6):955-961

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Arthritis and cognitive impairment in older adults.
  • Adults aged 65 or older with arthritis may be at increased risk for cognitive impairment [cognitive impairment but not dementia (CIND) or dementia].
  • Studies have found associations between arthritis and cognition impairments; however, none have examined whether persons with arthritis develop cognitive impairments at higher rates than those without arthritis.
  • Using data from the Health and Retirement Study, we estimated the prevalence of cognitive impairments in older adults with and without arthritis, and examined associations between arthritis status and cognitive impairments.
  • We calculated incidence density ratios (IDRs) using generalized estimating equations to estimate associations between arthritis and cognitive impairments adjusting for age, sex, race/ethnicity, marital status, education, income, depression, obesity, smoking, the number of chronic conditions, physical activity, and birth cohort.
  • The prevalence of CIND and dementia did not significantly differ between those with and without arthritis (CIND: 20.8%, 95% CI 19.7-21.9 vs. 18.3%, 95% CI 16.8-19.8; dementia: 5.2% 95% CI 4.6-5.8 vs. 5.1% 95% CI 4.3-5.9).
  • After covariate control, older adults with arthritis did not differ significantly from those without arthritis for either cognitive outcome (CIND IDR: 1.6, 95% CI = 0.9-2.9; dementia IDR: 1.1, 95% CI = 0.4-3.3) and developed cognitive impairments at a similar rate to those without arthritis.
  • Older adults with arthritis were not significantly more at risk to develop cognitive impairments and developed cognitive impairments at a similar rate as older adults without arthritis over 6 years.

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  • (PMID = 28337526.001).
  • [ISSN] 1437-160X
  • [Journal-full-title] Rheumatology international
  • [ISO-abbreviation] Rheumatol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Aging / Cognitive impairment but not dementia / Dementia / Epidemiology
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10. Chen S, Han K, Li H, Cen J, Yang Y, Wu H, Wei Q: Isogarcinol Extracted from Garcinia mangostana L. Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in Mice. J Agric Food Chem; 2017 Feb 01;65(4):846-857
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Isogarcinol (YDIS), a natural compound extracted from Garcinia mangostana L., has a significant immunosuppressive effect on systemic lupus erythematosus and rheumatoid arthritis.
  • Moreover, the expression of genes involving the interleukin-23 (IL-23)/T-helper 17 (Th17) axis was significantly inhibited in the dorsal skin of the YDIS-treated mice, as was that of the other pro-inflammatory factors TNF-α, IL-2, and even interferon (IFN)-γ.
  • Furthermore, YDIS prevented the abnormal distribution of T cell types and suppressed the differentiation of CD4<sup>+</sup> T cells into Th17 cells in the spleens of mice exposed to imiquimod.
  • It also strongly inhibited inflammatory factor expression in lipopolysaccharide (LPS)-stimulated HaCaT cells.
  • [MeSH-minor] Animals. Disease Models, Animal. Female. Humans. Interleukin-2 / genetics. Interleukin-2 / immunology. Interleukin-23 / genetics. Interleukin-23 / immunology. Mice. Mice, Inbred C57BL. T-Lymphocytes, Regulatory / drug effects. T-Lymphocytes, Regulatory / immunology. Th17 Cells / drug effects. Th17 Cells / immunology. Tumor Necrosis Factor-alpha

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  • (PMID = 28081600.001).
  • [ISSN] 1520-5118
  • [Journal-full-title] Journal of agricultural and food chemistry
  • [ISO-abbreviation] J. Agric. Food Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Interleukin-2; 0 / Interleukin-23; 0 / Plant Extracts; 0 / Tumor Necrosis Factor-alpha; P1QW714R7M / imiquimod
  • [Keywords] NOTNLM ; HaCaT / T-helper 17 cell / cyclosporine A / imiquimod-induced / isogarcinol / psoriasis / regulatory T cell
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