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Items 1 to 10 of about 61786
1. Zhao P, Chen KL, Zhang GL, Deng GR, Li J: Pharmacological Basis for Use of <i>Selaginella moellendorffii</i> in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition. Evid Based Complement Alternat Med; 2017;2017:2103254

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacological Basis for Use of <i>Selaginella moellendorffii</i> in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition.
  • This study was aimed at evaluating the effects of <i>Selaginella moellendorffii</i> Hieron. (SM) on gouty arthritis and getting an insight of the possible mechanisms.
  • The paw oedema, the neutrophil accumulation, inflammatory mediators, lipid peroxidation, and histopathological changes of the joints were analyzed in gouty arthritis rat model, and the kidney injury and serum urate were detected in hyperuricemic mice.
  • The high dose of SM extract could significantly prevent the paw swelling, reduce gouty joint inflammatory features, reduce the release of IL-1<i>β</i> and TNF-<i>α</i>, lower malondialdehyde (MDA) and myeloperoxidase (MPO) levels, and increase superoxide dismutase (SOD) level (<i>P</i> < 0.01).

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  • (PMID = 28250791.001).
  • [ISSN] 1741-427X
  • [Journal-full-title] Evidence-based complementary and alternative medicine : eCAM
  • [ISO-abbreviation] Evid Based Complement Alternat Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. Curtis JR, Schulze-Koops H, Takiya L, Mebus CA, Terry KK, Biswas P, Jones TV: Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis. Clin Exp Rheumatol; 2017 Jan 04;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Efficacy and safety of tofacitinib in older and younger patients with rheumatoid arthritis.
  • OBJECTIVES: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA).

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  • (PMID = 28079500.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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3. Mbiantcha M, Almas J, Shabana SU, Nida D, Aisha F: Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund's adjuvant-induced arthritis in rats. BMC Complement Altern Med; 2017 Feb 15;17(1):111
MedlinePlus Health Information. consumer health - Rheumatoid Arthritis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund's adjuvant-induced arthritis in rats.
  • BACKGROUND: Rheumatoid arthritis, disease of unknown causes is a rheumatic and autoimmune pathology, recognised for its increasing frequency and its adverse consequences.
  • It is a disease that occurs in most cases between 50 and 60 years and women are more affected than men.
  • This study aimed at evaluating immunomodulatory and anti-arthritis capacity of aqueous and methanol extracts of stem bark of Piptadeniastrum africanum (Mimosaceae).
  • METHODS: ROS production from phagocytes, proliferation of T-cells, TNF-α and IL-1β production and cytotoxicity were performed by using chemiluminescence technique, liquid scintillation counter, ELISA and MTT assay, respectively.
  • Anti-arthritic activity was evaluated using a model of adjuvant induced arthritis.
  • Piptadeniastrum africanum also significantly exhibited antiarthritic activity in complete Freund's adjuvant induced arthritis in rat associated with a significant anti-inflammatory and anti-hyperalgesia activity.
  • CONCLUSIONS: Immunomodulatory, anti-inflammatory, antihyperalgesia and anti-arthritis potential revealed in this study approve that, Piptadeniastrum africanum is a plant rich in compounds with anti-arthritic properties.
  • [MeSH-major] Angiosperms. Anti-Inflammatory Agents / therapeutic use. Antirheumatic Agents / therapeutic use. Arthritis, Experimental / drug therapy. Arthritis, Rheumatoid / drug therapy. Phytotherapy. Plant Extracts / therapeutic use

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  • (PMID = 28202019.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents; 0 / Antioxidants; 0 / Antirheumatic Agents; 0 / Immunologic Factors; 0 / Interleukin-1beta; 0 / Plant Extracts; 0 / Reactive Oxygen Species; 0 / Tumor Necrosis Factor-alpha; 9007-81-2 / Freund's Adjuvant
  • [Keywords] NOTNLM ; Cytotoxicity / Immunomodulation / Oxidative burst / Piptadeniastrum africanum / Rheumatoid arthritis / T-cell proliferation
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4. Chen Y, Wang QW, Zuo J, Chen JW, Li X: Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice. BMC Complement Altern Med; 2017 Jan 05;17(1):11
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  • [Title] Anti-arthritic activity of ethanol extract of Claoxylon indicum on Freund's complete adjuvant-induced arthritis in mice.
  • BACKGROUND: Claoxylon indicum Hassk. (Euphorbiaceae), named Diu Le Bang, have functions of dehumidification and relieving swelling pain, and is used as a folk medicine to treat Rheumatoid arthritis (RA), lumbocrural pain and foot edema in the south of China.
  • The aim of the present study was to investigate the anti-arthritic activity of the ethanol extract of Claoxylon indicum (CIE) on mice with adjuvant induced joint arthritis.
  • METHODS: Adjuvant arthritis was induced in mice by subcutaneous injection of complete Freund's adjuvant into the plantar surface of right hind paw.
  • Arthritis severity was evaluated by arthritic score, hind paws oedema and spleen index, and histological examinations.
  • RESULTS: CIE administration (0.4 and 0.8 g/kg) suppressed the inflammatory responses in the joints of adjuvant-induced arthritis (AIA) mice, suggested by the modulatory effects on paw swelling, hyperplasia of lymphatic tissues and synovial membrane.
  • [MeSH-major] Antirheumatic Agents / administration & dosage. Arthritis, Experimental / drug therapy. Drugs, Chinese Herbal / administration & dosage. Euphorbiaceae / chemistry

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  • (PMID = 28056924.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Drugs, Chinese Herbal; 0 / Interleukin-1beta; 0 / Tumor Necrosis Factor-alpha; 3K9958V90M / Ethanol; 9007-81-2 / Freund's Adjuvant
  • [Keywords] NOTNLM ; Adjuvant arthritis / Claoxylon indicum / Inflammation / Rheumatoid arthritis (RA)
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5. Hamidpour R, Hamidpour S, Hamidpour M, Shahlari M, Sohraby M, Shahlari N, Hamidpour R: Russian olive (&lt;i&gt;Elaeagnus angustifolia&lt;/i&gt; L.): From a variety of traditional medicinal applications to its novel roles as active antioxidant, anti-inflammatory, anti-mutagenic and analgesic agent. J Tradit Complement Med; 2017 Jan;7(1):24-29

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Russian olive (<i>Elaeagnus angustifolia</i> L.): From a variety of traditional medicinal applications to its novel roles as active antioxidant, anti-inflammatory, anti-mutagenic and analgesic agent.
  • The use of fruit powder and extract of <i>E. angustifolia</i> L. have shown to be effective in alleviating pain in patients with rheumatoid arthritis and also in reducing the healing time of wounds in injured person.
  • In addition, some recent reports have indicated the anti-oxidant, anti-inflammatory, antimicrobial, anticancer and some other properties of oleaster plant.

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  • (PMID = 28053884.001).
  • [Journal-full-title] Journal of traditional and complementary medicine
  • [ISO-abbreviation] J Tradit Complement Med
  • [Language] eng
  • [Publication-type] Review; Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Anti-cancer / Anti-inflammation / Anti-microbial / Anti-oxidant / Russian olive
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6. Talotta R, Atzeni F, Batticciotto A, Benucci M, Bongiovanni S, Sarzi-Puttini P: Biological Agents In Rheumatoid Arthritis: A Cross-Link Between Immune Tolerance And Immune Surveillance. Curr Rheumatol Rev; 2016 Dec 30;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Biological Agents In Rheumatoid Arthritis: A Cross-Link Between Immune Tolerance And Immune Surveillance.
  • : The biological drugs have all been successfully used to treat rheumatoid arthritis (RA) and have led to fair rates of clinical remission; however, the possible occurrence of adverse events such as infectious diseases or cancers means that the patients undergoing treatment need to be closely monitored.

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  • (PMID = 28034349.001).
  • [ISSN] 1875-6360
  • [Journal-full-title] Current rheumatology reviews
  • [ISO-abbreviation] Curr Rheumatol Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United Arab Emirates
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7. Martínez-González CL, Martínez L, Martínez-Ortiz EJ, González-Trujano ME, Déciga-Campos M, Ventura-Martínez R, Díaz-Reval I: Moringa oleifera, a species with potential analgesic and anti-inflammatory activities. Biomed Pharmacother; 2017 Mar;87:482-488
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  • [Title] Moringa oleifera, a species with potential analgesic and anti-inflammatory activities.
  • The present study was undertaken to examine the antinociceptive and anti-inflammatory spectrum of M. oleifera leaf extracts discriminating the constituents' nature by using different kind of experimental models in rats.
  • Pharmacological evaluation of a non-polar and/or polar extracts at several doses (30-300mg/kg, p.o.) was explored through experimental nociception using formalin test, carrageenan-induced paw edema and arthritis with subcutaneous injection of collagen in rats.
  • Not only polar (from 30 or 100mg/kg, p.o.) but also non-polar extract produced significant inhibition of the nociceptive behavior with major efficacy in the inflammatory response in different assessed experimental models.
  • [MeSH-major] Analgesics / pharmacology. Anti-Inflammatory Agents / pharmacology. Edema / drug therapy. Moringa oleifera / chemistry. Pain / drug therapy

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  • [Copyright] Copyright © 2016 Elsevier Masson SAS. All rights reserved.
  • (PMID = 28073097.001).
  • [ISSN] 1950-6007
  • [Journal-full-title] Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  • [ISO-abbreviation] Biomed. Pharmacother.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents; 0 / Glucosides; 0 / Kaempferols; 0 / Phytochemicals; 0 / Plant Extracts; 731P2LE49E / kaempferol
  • [Keywords] NOTNLM ; Antinociception (major topic) / Chlorogenic acid (major topic) / Folk medicine (major topic) / Kaempferol-3-glucoside (major topic) / Moringa oleifera (major topic) / Morphology (major topic) / Scanning electronic microscopy (major topic)
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8. Yang M, Guo MY, Luo Y, Yun MD, Yan J, Liu T, Xiao CH: Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial. Chin J Integr Med; 2016 Dec 29;
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial.
  • OBJECTIVE: To investigate the effect and safety of the complementary use of the extract of Artemisia annua L. (EAA) on treating active rheumatoid arthritis (RA).

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  • (PMID = 28035541.001).
  • [ISSN] 1672-0415
  • [Journal-full-title] Chinese journal of integrative medicine
  • [ISO-abbreviation] Chin J Integr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Keywords] NOTNLM ; Artemisia annua / Chinese medicine / leflflunomide / methotrexate / rheumatoid arthritis
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9. Gao S, Wang Q, Tian XH, Li HL, Shen YH, Xu XK, Wu GZ, Hu ZL, Zhang WD: Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis. J Ethnopharmacol; 2017 Jan 20;196:39-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis.
  • BACKGROUNDS: Inula helenium L. is an herb with anti-inflammatory properties.
  • However, the anti-inflammatory effects of SL-containing extracts of I. helenium have not been explored.
  • Here we prepared total SLs from I. helenium (TSL-IHL), analyzed its chemical constituents, and performed cellular and animal studies to evaluate its anti-inflammatory activities.
  • Its in vitro effects on the activation of signaling pathways and expression of inflammatory genes were examined by western blotting and quantitative real-time PCR, respectively, and compared with those of AL and IAL.
  • Its in vivo anti-inflammatory effects were evaluated in adjuvant- and collagen-induced arthritis rat models.
  • Oral administration of TSL-IHL at 12.5-50mg/kg could dose-dependently alleviate the arthritic severity and paw swelling in either developing or developed phases of arthritis of rats induced by adjuvant or collagen CONCLUSIONS: These results indicated potentials of TSL-IHL in prevention and therapy of rheumatoid arthritis.

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  • [Copyright] Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 27988396.001).
  • [ISSN] 1872-7573
  • [Journal-full-title] Journal of ethnopharmacology
  • [ISO-abbreviation] J Ethnopharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Keywords] NOTNLM ; Anti-inflammatory / Inula helenium L. / Rheumatoid arthritis / Total sesquiterpene lactones
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10. Johari AN, Hampannavar A, Johari RA, Dhawale AA: Coxa vara in postseptic arthritis of the hip in children. J Pediatr Orthop B; 2017 Feb 01;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coxa vara in postseptic arthritis of the hip in children.

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  • (PMID = 28151779.001).
  • [ISSN] 1473-5865
  • [Journal-full-title] Journal of pediatric orthopedics. Part B
  • [ISO-abbreviation] J Pediatr Orthop B
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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